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Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses

As influenza A viruses remain a major threat to human health worldwide, the discovery of broadly neutralizing monoclonal antibodies that recognize conserved epitopes would facilitate the development of antibody-based therapeutic strategies. Here we report that a V(H)4-4-encoded human mAb named 3E1 c...

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Detalles Bibliográficos
Autores principales: Wang, Wenshuai, Sun, Xiaoyu, Li, Yanbing, Su, Jinpeng, Ling, Zhiyang, Zhang, Tianlong, Wang, Fang, Zhang, Hong, Chen, Hualan, Ding, Jianping, Sun, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477490/
https://www.ncbi.nlm.nih.gov/pubmed/27910950
http://dx.doi.org/10.1038/ncomms13577