Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres

Cytoskeletal mechanics regulates cell morphodynamics and many physiological processes. While contractility is known to be largely RhoA-dependent, the process by which localized biochemical signals are translated into cell-level responses is poorly understood. Here we combine optogenetic control of R...

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Detalles Bibliográficos
Autores principales: Oakes, Patrick W., Wagner, Elizabeth, Brand, Christoph A., Probst, Dimitri, Linke, Marco, Schwarz, Ulrich S., Glotzer, Michael, Gardel, Margaret L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477492/
https://www.ncbi.nlm.nih.gov/pubmed/28604737
http://dx.doi.org/10.1038/ncomms15817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477492/
https://www.ncbi.nlm.nih.gov/pubmed/28604737
http://dx.doi.org/10.1038/ncomms15817

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