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Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres
Cytoskeletal mechanics regulates cell morphodynamics and many physiological processes. While contractility is known to be largely RhoA-dependent, the process by which localized biochemical signals are translated into cell-level responses is poorly understood. Here we combine optogenetic control of R...
Autores principales: | Oakes, Patrick W., Wagner, Elizabeth, Brand, Christoph A., Probst, Dimitri, Linke, Marco, Schwarz, Ulrich S., Glotzer, Michael, Gardel, Margaret L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477492/ https://www.ncbi.nlm.nih.gov/pubmed/28604737 http://dx.doi.org/10.1038/ncomms15817 |
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