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Structural basis for conductance through TRIC cation channels

Mammalian TRICs function as K(+)-permeable cation channels that provide counter ions for Ca(2+) handling in intracellular stores. Here we describe the structures of two prokaryotic homologues, archaeal SaTRIC and bacterial CpTRIC, showing that TRIC channels are symmetrical trimers with transmembrane...

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Detalles Bibliográficos
Autores principales: Su, Min, Gao, Feng, Yuan, Qi, Mao, Yang, Li, De-lin, Guo, Youzhong, Yang, Cheng, Wang, Xiao-hui, Bruni, Renato, Kloss, Brian, Zhao, Hong, Zeng, Yang, Zhang, Fa-ben, Marks, Andrew R, Hendrickson, Wayne A, Chen, Yu-hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477506/
https://www.ncbi.nlm.nih.gov/pubmed/28524849
http://dx.doi.org/10.1038/ncomms15103