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Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling

Trabeculation is crucial for cardiac muscle growth in vertebrates. This process requires the Erbb2/4 ligand Neuregulin (Nrg), secreted by the endocardium, as well as blood flow/cardiac contractility. Here, we address two fundamental, yet unresolved, questions about cardiac trabeculation: why does it...

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Detalles Bibliográficos
Autores principales: Rasouli, S. Javad, Stainier, Didier Y. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477525/
https://www.ncbi.nlm.nih.gov/pubmed/28485381
http://dx.doi.org/10.1038/ncomms15281