ZEB1 induces ER-α promoter hypermethylation and confers antiestrogen resistance in breast cancer

Antiestrogen resistance is a major obstacle to endocrine therapy for breast cancers. Although reduced estrogen receptor-α (ER-α) expression is a known contributing factor to antiestrogen resistance, the mechanisms of ER-α downregulation in antiestrogen resistance are not fully understood. Here, we r...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jianbo, Zhou, Chen, Jiang, Huimin, Liang, Lin, Shi, Wen, Zhang, Quansheng, Sun, Peiqing, Xiang, Rong, Wang, Yue, Yang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477580/
https://www.ncbi.nlm.nih.gov/pubmed/28383555
http://dx.doi.org/10.1038/cddis.2017.154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477580/
https://www.ncbi.nlm.nih.gov/pubmed/28383555
http://dx.doi.org/10.1038/cddis.2017.154

Ejemplares similares