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ZEB1 induces ER-α promoter hypermethylation and confers antiestrogen resistance in breast cancer

Antiestrogen resistance is a major obstacle to endocrine therapy for breast cancers. Although reduced estrogen receptor-α (ER-α) expression is a known contributing factor to antiestrogen resistance, the mechanisms of ER-α downregulation in antiestrogen resistance are not fully understood. Here, we r...

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Detalles Bibliográficos
Autores principales:	Zhang, Jianbo, Zhou, Chen, Jiang, Huimin, Liang, Lin, Shi, Wen, Zhang, Quansheng, Sun, Peiqing, Xiang, Rong, Wang, Yue, Yang, Shuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477580/ https://www.ncbi.nlm.nih.gov/pubmed/28383555 http://dx.doi.org/10.1038/cddis.2017.154

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