Silencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancer

NKG2D is one of the major activating receptors of natural killer (NK) cells and binds to several ligands (NKG2DLs). NKG2DLs are expressed on malignant cells and sensitize them to early elimination by cytotoxic lymphocytes. We investigated the clinical importance of NKG2DLs and the mechanism of NKG2D...

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Detalles Bibliográficos
Autores principales: Shen, Jiaying, Pan, Jie, Du, Chengyong, Si, Wengong, Yao, Minya, Xu, Liang, Zheng, Huilin, Xu, Mingjie, Chen, Danni, Wang, Shu, Fu, Peifen, Fan, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477582/
https://www.ncbi.nlm.nih.gov/pubmed/28383557
http://dx.doi.org/10.1038/cddis.2017.158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477582/
https://www.ncbi.nlm.nih.gov/pubmed/28383557
http://dx.doi.org/10.1038/cddis.2017.158

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