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Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain
Oxidative modification of the voltage-gated potassium (K(+)) channel KCNB1 promotes apoptosis in the neurons of cortex and hippocampus through a signaling pathway mediated by Src tyrosine kinases. How oxidation of the channel is transduced into Src recruitment and activation, however, was not known....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477583/ https://www.ncbi.nlm.nih.gov/pubmed/28383553 http://dx.doi.org/10.1038/cddis.2017.160 |