Induction of autophagy by spermidine is neuroprotective via inhibition of caspase 3-mediated Beclin 1 cleavage

Spermidine, a natural polyamine presented widely in mammalian cells, has been implicated to extend the lifespan of several model organisms by inducing autophagy. However, the effect of spermidine against neuronal damage has not yet been fully determined. In this study, neuronal cell injury was induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yi, Chen, Sicong, Zhang, Yuqing, Lin, Xiaoxia, Song, Yiyin, Xue, Zhaoliang, Qian, Haoran, Wang, Shanshan, Wan, Guihua, Zheng, Xiaoxiang, Zhang, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477584/
https://www.ncbi.nlm.nih.gov/pubmed/28383560
http://dx.doi.org/10.1038/cddis.2017.161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477584/
https://www.ncbi.nlm.nih.gov/pubmed/28383560
http://dx.doi.org/10.1038/cddis.2017.161

Ejemplares similares