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Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcription and associated T-cell effector functions

CD95/Fas ligand (FasL) is a cell death-promoting member of the tumor necrosis factor family with important functions in the regulation of T-cell homeostasis and cytotoxicity. In T cells, FasL expression is tightly regulated on a transcriptional level involving a complex set of different transcriptio...

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Detalles Bibliográficos
Autores principales: Schwaderer, Juliane, Gaiser, Ann-Kathrin, Phan, Truong San, Delgado, MEugenia, Brunner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477591/
https://www.ncbi.nlm.nih.gov/pubmed/28406481
http://dx.doi.org/10.1038/cddis.2017.173