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Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcription and associated T-cell effector functions
CD95/Fas ligand (FasL) is a cell death-promoting member of the tumor necrosis factor family with important functions in the regulation of T-cell homeostasis and cytotoxicity. In T cells, FasL expression is tightly regulated on a transcriptional level involving a complex set of different transcriptio...
Autores principales: | Schwaderer, Juliane, Gaiser, Ann-Kathrin, Phan, Truong San, Delgado, MEugenia, Brunner, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477591/ https://www.ncbi.nlm.nih.gov/pubmed/28406481 http://dx.doi.org/10.1038/cddis.2017.173 |
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