Synovial cell death is regulated by TNF-α-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1α

B-cell activating factor (BAFF) has a role in the maturation and maintenance of B cells and is associated with rheumatoid arthritis (RA). Here, we investigated whether tumor necrosis factor (TNF)-α-induced BAFF expression controls the survival of fibroblast-like synoviocytes (FLS) and whether their...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jae-Wook, Lee, Jiyoung, Um, Sung Hee, Moon, Eun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477592/
https://www.ncbi.nlm.nih.gov/pubmed/28383556
http://dx.doi.org/10.1038/cddis.2017.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477592/
https://www.ncbi.nlm.nih.gov/pubmed/28383556
http://dx.doi.org/10.1038/cddis.2017.26

Ejemplares similares