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miR-10a suppresses colorectal cancer metastasis by modulating the epithelial-to-mesenchymal transition and anoikis

MicroRNAs (miRNAs) have a critical role in tumorigenesis and metastasis, which are major obstacles of cancer therapy. However, the role of miRNAs in colorectal cancer (CRC) metastasis remains poorly understood. Here, we found that miRNA-10a (miR-10a) was upregulated in primary CRC tissues and cell l...

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Detalles Bibliográficos
Autores principales: Liu, Yankun, Zhang, Yingnan, Wu, Haidong, Li, Yufeng, Zhang, Yi, Liu, Min, Li, Xin, Tang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477594/
https://www.ncbi.nlm.nih.gov/pubmed/28383561
http://dx.doi.org/10.1038/cddis.2017.61