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miR-10a suppresses colorectal cancer metastasis by modulating the epithelial-to-mesenchymal transition and anoikis

MicroRNAs (miRNAs) have a critical role in tumorigenesis and metastasis, which are major obstacles of cancer therapy. However, the role of miRNAs in colorectal cancer (CRC) metastasis remains poorly understood. Here, we found that miRNA-10a (miR-10a) was upregulated in primary CRC tissues and cell l...

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Dades bibliogràfiques
Autors principals: Liu, Yankun, Zhang, Yingnan, Wu, Haidong, Li, Yufeng, Zhang, Yi, Liu, Min, Li, Xin, Tang, Hua
Format: Online Article Text
Idioma:English
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477594/
https://www.ncbi.nlm.nih.gov/pubmed/28383561
http://dx.doi.org/10.1038/cddis.2017.61