Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells

Atopic dermatitis (AD) is a chronic Th2 type inflammatory skin disorder. Here we report that MyD88 signaling is crucial in the pathogenesis of experimental AD induced by vitamin D3 analog MC903. The clinical signs and inflammation caused by MC903 are drastically reduced in MyD88(−/−) mice with dimin...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Changwei, Maillet, Isabelle, Mackowiak, Claire, Viala, Camille, Di Padova, Franco, Li, Mei, Togbe, Dieudonnée, Quesniaux, Valérie, Lai, Yuping, Ryffel, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477596/
https://www.ncbi.nlm.nih.gov/pubmed/28383552
http://dx.doi.org/10.1038/cddis.2017.90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477596/
https://www.ncbi.nlm.nih.gov/pubmed/28383552
http://dx.doi.org/10.1038/cddis.2017.90

Ejemplares similares