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Long-term observation reveals high-frequency engraftment of human acute myeloid leukemia in immunodeficient mice

Repopulation of immunodeficient mice remains the primary method for functional assessment of human acute myeloid leukemia. Published data report engraftment in ~40–66% of cases, mostly of intermediate- or poor-risk subtypes. Here we report that extending follow-up beyond the standard analysis endpoi...

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Detalles Bibliográficos
Autores principales: Paczulla, Anna M., Dirnhofer, Stephan, Konantz, Martina, Medinger, Michael, Salih, Helmut R., Rothfelder, Kathrin, Tsakiris, Dimitrios A., Passweg, Jakob R., Lundberg, Pontus, Lengerke, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477604/
https://www.ncbi.nlm.nih.gov/pubmed/28183848
http://dx.doi.org/10.3324/haematol.2016.153528