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A centrosome clustering protein, KIFC1, predicts aggressive disease course in serous ovarian adenocarcinomas
BACKGROUND: Amplified centrosomes are widely recognized as a hallmark of cancer. Although supernumerary centrosomes would be expected to compromise cell viability by yielding multipolar spindles that results in death-inducing aneuploidy, cancer cells suppress multipolarity by clustering their extra...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477851/ https://www.ncbi.nlm.nih.gov/pubmed/26992853 http://dx.doi.org/10.1186/s13048-016-0224-0 |