Cargando…
A centrosome clustering protein, KIFC1, predicts aggressive disease course in serous ovarian adenocarcinomas
BACKGROUND: Amplified centrosomes are widely recognized as a hallmark of cancer. Although supernumerary centrosomes would be expected to compromise cell viability by yielding multipolar spindles that results in death-inducing aneuploidy, cancer cells suppress multipolarity by clustering their extra...
Autores principales: | Mittal, Karuna, Choi, Da Hoon, Klimov, Sergey, Pawar, Shrikant, Kaur, Ramneet, Mitra, Anirban K., Gupta, Meenakshi V., Sams, Ralph, Cantuaria, Guilherme, Rida, Padmashree C. G., Aneja, Ritu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477851/ https://www.ncbi.nlm.nih.gov/pubmed/26992853 http://dx.doi.org/10.1186/s13048-016-0224-0 |
Ejemplares similares
-
Rampant centrosome amplification underlies more aggressive disease course of triple negative breast cancers
por: Pannu, Vaishali, et al.
Publicado: (2015) -
Multi-institutional study of nuclear KIFC1 as a biomarker of poor prognosis in African American women with triple-negative breast cancer
por: Ogden, Angela, et al.
Publicado: (2017) -
KIFCI, a novel putative prognostic biomarker for ovarian adenocarcinomas: delineating protein interaction networks and signaling circuitries
por: Pawar, Shrikant, et al.
Publicado: (2014) -
Hypoxia-Induced Centrosome Amplification Underlies Aggressive Disease Course in HPV-Negative Oropharyngeal Squamous Cell Carcinomas
por: Mittal, Karuna, et al.
Publicado: (2020) -
Prognostic value of CA20, a score based on centrosome amplification-associated genes, in breast tumors
por: Ogden, Angela, et al.
Publicado: (2017)