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Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1

BACKGROUND: BMAL1 is a transcriptional activator of the molecular clock feedback network. Besides its role in generating circadian rhythms, it has also been shown to be involved in the modulation of cell proliferation, autophagy and cancer cell invasion. However, the role of BMAL1 in pulmonary fibro...

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Detalles Bibliográficos
Autores principales: Dong, Chunmin, Gongora, Rafael, Sosulski, Meredith L., Luo, Fayong, Sanchez, Cecilia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477854/
https://www.ncbi.nlm.nih.gov/pubmed/26753996
http://dx.doi.org/10.1186/s12931-016-0320-0