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RNA editing by the host ADAR system affects the molecular evolution of the Zika virus

Zika virus (ZIKV) is a mosquito‐transmitted flavivirus, linked to microcephaly and fetal death in humans. Here, we investigate whether host‐mediated RNA editing of adenosines (ADAR) plays a role in the molecular evolution of ZIKV. Using complete coding sequences for the ZIKV polyprotein, we show tha...

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Detalles Bibliográficos
Autores principales: Piontkivska, Helen, Frederick, Madeline, Miyamoto, Michael M., Wayne, Marta L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478085/
https://www.ncbi.nlm.nih.gov/pubmed/28649357
http://dx.doi.org/10.1002/ece3.3033