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Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species

It has been proposed that aging results from the lifelong accumulation of intracellular damage via reactions with reactive oxygen species (ROS). Metallothioneins are conserved cysteine-rich proteins that function as efficient ROS scavengers and may affect longevity. To better understand mechanisms c...

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Detalles Bibliográficos
Autores principales: Hall, Julie A., McElwee, Matthew K., Freedman, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478092/
https://www.ncbi.nlm.nih.gov/pubmed/28632756
http://dx.doi.org/10.1371/journal.pone.0177432