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High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance
Antibiotic-resistant infections kill approximately 23,000 people and cost $20,000,000,000 each year in the United States alone despite the widespread use of small-molecule antimicrobial combination therapy. Antibiotic combinations typically have an additive effect: the efficacy of the combination ma...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478098/ https://www.ncbi.nlm.nih.gov/pubmed/28632788 http://dx.doi.org/10.1371/journal.pbio.2001644 |