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Trimetazidine therapy for diabetic mouse hearts subjected to ex vivo acute heart failure

Acute heart failure (AHF) is the most common primary diagnosis for hospitalized heart diseases in Africa. As increased fatty acid β-oxidation (FAO) during heart failure triggers detrimental effects on the myocardium, we hypothesized that trimetazidine (TMZ) (partial FAO inhibitor) offers cardioprote...

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Detalles Bibliográficos
Autores principales: Breedt, Emilene, Lacerda, Lydia, Essop, M. Faadiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478112/
https://www.ncbi.nlm.nih.gov/pubmed/28632748
http://dx.doi.org/10.1371/journal.pone.0179509