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A conserved role for the ESCRT membrane budding complex in LINE retrotransposition

Long interspersed nuclear element-1s (LINE-1s, or L1s) are an active family of retrotransposable elements that continue to mutate mammalian genomes. Despite the large contribution of L1 to mammalian genome evolution, we do not know where active L1 particles (particles in the process of retrotranspos...

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Detalles Bibliográficos
Autores principales: Horn, Axel V., Celic, Ivana, Dong, Chun, Martirosyan, Irena, Han, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478143/
https://www.ncbi.nlm.nih.gov/pubmed/28586350
http://dx.doi.org/10.1371/journal.pgen.1006837