Serotonin Signaling Through the 5-HT(1B) Receptor and NADPH Oxidase 1 in Pulmonary Arterial Hypertension

OBJECTIVE—: Serotonin can induce human pulmonary artery smooth muscle cell (hPASMC) proliferation through reactive oxygen species (ROS), influencing the development of pulmonary arterial hypertension (PAH). We hypothesize that in PASMCs, serotonin induces oxidative stress through NADPH-oxidase–deriv...

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Detalles Bibliográficos
Autores principales: Hood, Katie Y., Mair, Kirsty M., Harvey, Adam P., Montezano, Augusto C., Touyz, Rhian M., MacLean, Margaret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478178/
https://www.ncbi.nlm.nih.gov/pubmed/28473438
http://dx.doi.org/10.1161/ATVBAHA.116.308929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478178/
https://www.ncbi.nlm.nih.gov/pubmed/28473438
http://dx.doi.org/10.1161/ATVBAHA.116.308929

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