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The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

Despite being overexpressed in different tumor entities, RIO kinases are hardly characterized in mammalian cells. We investigated the role of these atypical kinases in different cancer cells. Using isogenic colon-, breast- and lung cancer cell lines, we demonstrate that knockdown of RIOK1, but not o...

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Detalles Bibliográficos
Autores principales: Weinberg, Florian, Reischmann, Nadine, Fauth, Lisa, Taromi, Sanaz, Mastroianni, Justin, Köhler, Martin, Halbach, Sebastian, Becker, Andrea C., Deng, Niantao, Schmitz, Tatjana, Uhl, Franziska Maria, Herbener, Nicola, Riedel, Bianca, Beier, Fabian, Swarbrick, Alexander, Lassmann, Silke, Dengjel, Jörn, Zeiser, Robert, Brummer, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478185/
https://www.ncbi.nlm.nih.gov/pubmed/28499923
http://dx.doi.org/10.1016/j.ebiom.2017.04.015