Hypercholesterolemia Causes Circadian Dysfunction: A Potential Risk Factor for Cardiovascular Disease

Hypercholesterolemia is a well-known risk factor for a wide range of diseases in developed countries. Here, we report that mice lacking functional LDLR (low density lipoprotein receptor), an animal model of human familial hypercholesterolemia, show circadian abnormalities. In free running behavioral...

Descripción completa

Detalles Bibliográficos
Autores principales: Akashi, Makoto, Matsumura, Ritsuko, Matsuo, Takahiro, Kubo, Yuki, Komoda, Hiroshi, Node, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478205/
https://www.ncbi.nlm.nih.gov/pubmed/28499924
http://dx.doi.org/10.1016/j.ebiom.2017.04.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478205/
https://www.ncbi.nlm.nih.gov/pubmed/28499924
http://dx.doi.org/10.1016/j.ebiom.2017.04.034

Ejemplares similares