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Hypercholesterolemia Causes Circadian Dysfunction: A Potential Risk Factor for Cardiovascular Disease
Hypercholesterolemia is a well-known risk factor for a wide range of diseases in developed countries. Here, we report that mice lacking functional LDLR (low density lipoprotein receptor), an animal model of human familial hypercholesterolemia, show circadian abnormalities. In free running behavioral...
Autores principales: | Akashi, Makoto, Matsumura, Ritsuko, Matsuo, Takahiro, Kubo, Yuki, Komoda, Hiroshi, Node, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478205/ https://www.ncbi.nlm.nih.gov/pubmed/28499924 http://dx.doi.org/10.1016/j.ebiom.2017.04.034 |
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