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BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer

Branched-chain amino acids catabolism plays an important role in human cancers. Colorectal cancer is the third most commonly diagnosed cancer in males and the second in females, and the new global incidence is over 1.2 million cases. The branched-chain α-keto acid dehydrogenase kinase (BCKDK) is a r...

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Detalles Bibliográficos
Autores principales: Xue, Peipei, Zeng, Fanfan, Duan, Qiuhong, Xiao, Juanjuan, Liu, Lin, Yuan, Ping, Fan, Linni, Sun, Huimin, Malyarenko, Olesya S., Lu, Hui, Xiu, Ruijuan, Liu, Shaoqing, Shao, Chen, Zhang, Jianmin, Yan, Wei, Wang, Zhe, Zheng, Jianyong, Zhu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478211/
https://www.ncbi.nlm.nih.gov/pubmed/28501528
http://dx.doi.org/10.1016/j.ebiom.2017.05.001