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The Role of Heterotypic DENV-specific CD8(+) T Lymphocytes in an Immunocompetent Mouse Model of Secondary Dengue Virus Infection

Dengue is the most prevalent arthropod-borne viral disease worldwide and is caused by the four dengue virus serotypes (DENV-1-4). Sequential heterologous DENV infections can be associated with severe disease manifestations. Here, we present an immunocompetent mouse model of secondary DENV infection...

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Detalles Bibliográficos
Autores principales: Talarico, Laura B., Batalle, Juan P., Byrne, Alana B., Brahamian, Jorge M., Ferretti, Adrián, García, Ayelén G., Mauri, Aldana, Simonetto, Carla, Hijano, Diego R., Lawrence, Andrea, Acosta, Patricio L., Caballero, Mauricio T., Paredes Rojas, Yésica, Ibañez, Lorena I., Melendi, Guillermina A., Rey, Félix A., Damonte, Elsa B., Harris, Eva, Polack, Fernando P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478214/
https://www.ncbi.nlm.nih.gov/pubmed/28483582
http://dx.doi.org/10.1016/j.ebiom.2017.04.033