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p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock

Sepsis is a major cause of morbidity and mortality in seriously ill patients and mitochondrial dysfunction is associated with poor outcomes in septic patients. Although interleukin-6 (IL-6) is a good prognostic marker for sepsis, the relationship between mitochondrial dysfunction and IL-6 remains po...

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Detalles Bibliográficos
Autores principales: Sasaki, Katsuhiko, Gotoh, Kazuhito, Miake, Sho, Setoyama, Daiki, Yagi, Mikako, Igami, Ko, Uchiumi, Takeshi, Kang, Donchon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478242/
https://www.ncbi.nlm.nih.gov/pubmed/28549777
http://dx.doi.org/10.1016/j.ebiom.2017.05.018