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p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock
Sepsis is a major cause of morbidity and mortality in seriously ill patients and mitochondrial dysfunction is associated with poor outcomes in septic patients. Although interleukin-6 (IL-6) is a good prognostic marker for sepsis, the relationship between mitochondrial dysfunction and IL-6 remains po...
Autores principales: | Sasaki, Katsuhiko, Gotoh, Kazuhito, Miake, Sho, Setoyama, Daiki, Yagi, Mikako, Igami, Ko, Uchiumi, Takeshi, Kang, Donchon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478242/ https://www.ncbi.nlm.nih.gov/pubmed/28549777 http://dx.doi.org/10.1016/j.ebiom.2017.05.018 |
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