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Computational design of ligand binding membrane receptors with high selectivity
Accurate modeling and design of protein-ligand interactions have broad applications in cell, synthetic biology and drug discovery but remain challenging without experimental protein structures. Here we developed an integrated protein homology modeling-ligand docking-protein design approach that reco...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478435/ https://www.ncbi.nlm.nih.gov/pubmed/28459439 http://dx.doi.org/10.1038/nchembio.2371 |