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Plasticity, dynamics, and inhibition of emerging tetracycline-resistance enzymes

While tetracyclines are an important class of antibiotics in agriculture and the clinic, their efficacy is threatened by increasing resistance. Resistance to tetracyclines can occur through efflux, ribosomal protection, or enzymatic inactivation. Surprisingly, tetracycline enzymatic inactivation has...

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Detalles Bibliográficos
Autores principales: Park, Jooyoung, Gasparrini, Andrew J., Reck, Margaret R., Symister, Chanez T., Elliott, Jennifer L., Vogel, Joseph P., Wencewicz, Timothy A., Dantas, Gautam, Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478473/
https://www.ncbi.nlm.nih.gov/pubmed/28481346
http://dx.doi.org/10.1038/nchembio.2376