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Plasticity, dynamics, and inhibition of emerging tetracycline-resistance enzymes
While tetracyclines are an important class of antibiotics in agriculture and the clinic, their efficacy is threatened by increasing resistance. Resistance to tetracyclines can occur through efflux, ribosomal protection, or enzymatic inactivation. Surprisingly, tetracycline enzymatic inactivation has...
Autores principales: | Park, Jooyoung, Gasparrini, Andrew J., Reck, Margaret R., Symister, Chanez T., Elliott, Jennifer L., Vogel, Joseph P., Wencewicz, Timothy A., Dantas, Gautam, Tolia, Niraj H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478473/ https://www.ncbi.nlm.nih.gov/pubmed/28481346 http://dx.doi.org/10.1038/nchembio.2376 |
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