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Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors

BACKGROUND: Evaluation of gene-based approaches to target human bone marrow aspirates in conditions of mechanical stimulation that aim at reproducing the natural joint environment may allow to develop improved treatments for articular cartilage injuries. In the present study, we investigated the pot...

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Detalles Bibliográficos
Autores principales: Venkatesan, Jagadeesh K., Frisch, Janina, Rey-Rico, Ana, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478551/
https://www.ncbi.nlm.nih.gov/pubmed/28634835
http://dx.doi.org/10.1186/s40634-017-0097-1