Cargando…
Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors
BACKGROUND: Evaluation of gene-based approaches to target human bone marrow aspirates in conditions of mechanical stimulation that aim at reproducing the natural joint environment may allow to develop improved treatments for articular cartilage injuries. In the present study, we investigated the pot...
Autores principales: | Venkatesan, Jagadeesh K., Frisch, Janina, Rey-Rico, Ana, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478551/ https://www.ncbi.nlm.nih.gov/pubmed/28634835 http://dx.doi.org/10.1186/s40634-017-0097-1 |
Ejemplares similares
-
TGF‐β gene transfer and overexpression via
rAAV vectors stimulates chondrogenic events in human bone marrow aspirates
por: Frisch, Janina, et al.
Publicado: (2016) -
Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates
por: Tao, Ke, et al.
Publicado: (2017) -
Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates
por: Frisch, Janina, et al.
Publicado: (2016) -
Peripheral blood aspirates overexpressing IGF‐I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes
por: Frisch, Janina, et al.
Publicado: (2017) -
Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells
por: Tao, Ke, et al.
Publicado: (2016)