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Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways

The Fanconi anemia pathway in coordination with homologous recombination is essential to repair interstrand crosslinks (ICLs) caused by cisplatin. TIP60 belongs to the MYST family of acetyltransferases and is involved in DNA repair and regulation of gene transcription. Although the physical interact...

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Detalles Bibliográficos
Autores principales: Su, Wen-Pin, Ho, Yen-Chih, Wu, Cheng-Kuei, Hsu, Sen-Huei, Shiu, Jia-Lin, Huang, Jheng-Cheng, Chang, Song-Bin, Chiu, Wen-Tai, Hung, Jan-Jong, Liu, Tsung-Lin, Wu, Wei-Sheng, Wu, Pei-Yu, Su, Wu-Chou, Chang, Jang-Yang, Liaw, Hungjiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478611/
https://www.ncbi.nlm.nih.gov/pubmed/28634400
http://dx.doi.org/10.1038/s41598-017-04223-5