Enhanced antiviral and antifibrotic effects of short hairpin RNAs targeting HBV and TGF-β in HBV-persistent mice

The hepatitis B virus (HBV) causes acute and chronic liver infection, which may lead to liver cirrhosis and hepatocellular carcinoma. Current treatments including interferons and nucleotide analogs, have limited therapeutic effects, underscoring the need to identify effective therapeutic options to...

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Detalles Bibliográficos
Autores principales: Ye, Lei, Kan, Fangming, Yan, Tao, Cao, Jiaqi, Zhang, Leiliang, Wu, Zhijian, Li, Wuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478661/
https://www.ncbi.nlm.nih.gov/pubmed/28634402
http://dx.doi.org/10.1038/s41598-017-04170-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478661/
https://www.ncbi.nlm.nih.gov/pubmed/28634402
http://dx.doi.org/10.1038/s41598-017-04170-1

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