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TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway

DNAX-activating protein of 12 kDa (DAP12) is a signaling adapter protein expressed in cells that participate in innate immune responses. By pairing with different triggering receptors expressed on myeloid cell (TREM) proteins, DAP12 can mediate both positive and negative cellular responses. In parti...

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Detalles Bibliográficos
Autores principales: Zhong, Li, Zhang, Zhen-Lian, Li, Xinxiu, Liao, Chunyan, Mou, Pengfei, Wang, Tingting, Wang, Zongqi, Wang, Zhe, Wei, Min, Xu, Huaxi, Bu, Guojun, Chen, Xiao-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478682/
https://www.ncbi.nlm.nih.gov/pubmed/28680398
http://dx.doi.org/10.3389/fnagi.2017.00204