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The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease

In neurons, but also in all other cells the complex proteostasis network is monitored and tightly regulated by the cellular protein quality control (PQC) system. Beyond folding of newly synthesized polypeptides and their refolding upon misfolding the PQC also manages the disposal of aberrant protein...

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Detalles Bibliográficos
Autores principales: Stürner, Elisabeth, Behl, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478690/
https://www.ncbi.nlm.nih.gov/pubmed/28680391
http://dx.doi.org/10.3389/fnmol.2017.00177