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Molecular Simulations of Carbohydrates with a Fucose-Binding Burkholderia ambifaria Lectin Suggest Modulation by Surface Residues Outside the Fucose-Binding Pocket

Burkholderia ambifaria is an opportunistic respiratory pathogen belonging to the Burkholderia cepacia complex, a collection of species responsible for the rapidly fatal cepacia syndrome in cystic fibrosis patients. A fucose-binding lectin identified in the B. ambifaria genome, BambL, is able to adhe...

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Detalles Bibliográficos
Autores principales: Dingjan, Tamir, Imberty, Anne, Pérez, Serge, Yuriev, Elizabeth, Ramsland, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478714/
https://www.ncbi.nlm.nih.gov/pubmed/28680402
http://dx.doi.org/10.3389/fphar.2017.00393