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Botulinum Neurotoxin A Injected Ipsilaterally or Contralaterally into the Striatum in the Rat 6-OHDA Model of Unilateral Parkinson’s Disease Differently Affects Behavior

Parkinson’s disease (PD) is one of the most frequent neurodegenerative disorders. The loss of dopaminergic neurons in the substantia nigra leads to a disinhibition of cholinergic interneurons in the striatum. Pharmacotherapeutical strategies of PD-related hypercholinism have numerous adverse side ef...

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Detalles Bibliográficos
Autores principales: Antipova, Veronica A., Holzmann, Carsten, Schmitt, Oliver, Wree, Andreas, Hawlitschka, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478737/
https://www.ncbi.nlm.nih.gov/pubmed/28680396
http://dx.doi.org/10.3389/fnbeh.2017.00119