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One-step purification and characterization of alginate lyase from a clinical Pseudomonas aeruginosa with destructive activity on bacterial biofilm

OBJECTIVE(S): Pseudomonas aeruginosa is a Gram-negative and aerobic rod bacterium that displays mucoid and non-mucoid phenotype. Mucoid strains secrete alginate, which is the main agent of biofilms in chronic P. aeruginosa infections, show high resistance to antibiotics; consequently, the biological...

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Detalles Bibliográficos
Autores principales: Ghadam, Parinaz, Akhlaghi, Fatemeh, Ali, Ahya Abdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478773/
https://www.ncbi.nlm.nih.gov/pubmed/28656080
http://dx.doi.org/10.22038/IJBMS.2017.8668