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MiR-570 inhibits cell proliferation and glucose metabolism by targeting IRS1 and IRS2 in human chronic myelogenous leukemia

OBJECTIVE(S): Chronic myelogenous leukemia (CML) is a chronic myeloproliferative disorder characterized by the accumulation of myeloid cells with a chromosomal translocation known as the Philadelphia chromosome. In this study, we investigated the roles of miR-570 in CML development. MATERIALS AND ME...

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Detalles Bibliográficos
Autores principales: Zhao, Hong, Liu, Fei, Jia, Ruichun, Chang, Huiying, Li, Haixia, Miao, Meijuan, Wang, Hui, Yang, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478775/
https://www.ncbi.nlm.nih.gov/pubmed/28656082
http://dx.doi.org/10.22038/IJBMS.2017.8671