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The Phosphatase Inhibitor Calyculin-A Impairs Clot Retraction, Platelet Activation, and Thrombin Generation

The aim of this study was to investigate the effect of the serine/threonine protein phosphatase inhibitor, calyculin-A (CLA), on clot formation and on the procoagulant activity of human platelets. Platelet-rich plasma (PRP) samples were preincubated with buffer or CLA and subsequently platelets were...

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Detalles Bibliográficos
Autores principales: Hudák, Renáta, Vincze, János, Csernoch, László, Beke Debreceni, Ildikó, Oláh, Tamás, Erdődi, Ferenc, Clemetson, Kenneth J., Kappelmayer, János
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478853/
https://www.ncbi.nlm.nih.gov/pubmed/28680886
http://dx.doi.org/10.1155/2017/9795271