Mitochondrial Uncoupler Prodrug of 2,4-Dinitrophenol, MP201, Prevents Neuronal Damage and Preserves Vision in Experimental Optic Neuritis

The ability of novel mitochondrial uncoupler prodrug of 2,4-dinitrophenol (DNP), MP201, to prevent neuronal damage and preserve visual function in an experimental autoimmune encephalomyelitis (EAE) model of optic neuritis was evaluated. Optic nerve inflammation, demyelination, and axonal loss are pr...

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Detalles Bibliográficos
Autores principales: Khan, Reas S., Dine, Kimberly, Geisler, John G., Shindler, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478871/
https://www.ncbi.nlm.nih.gov/pubmed/28680531
http://dx.doi.org/10.1155/2017/7180632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478871/
https://www.ncbi.nlm.nih.gov/pubmed/28680531
http://dx.doi.org/10.1155/2017/7180632

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