Alternative Evolutionary Pathways for Drug-Resistant Small Colony Variant Mutants in Staphylococcus aureus

Staphylococcus aureus is known to generate small colony variants (SCVs) that are resistant to aminoglycoside antibiotics and can cause persistent and recurrent infections. The SCV phenotype is unstable, and compensatory mutations lead to restored growth, usually with loss of resistance. However, the...

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Detalles Bibliográficos
Autores principales: Cao, Sha, Huseby, Douglas L., Brandis, Gerrit, Hughes, Diarmaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478891/
https://www.ncbi.nlm.nih.gov/pubmed/28634236
http://dx.doi.org/10.1128/mBio.00358-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478891/
https://www.ncbi.nlm.nih.gov/pubmed/28634236
http://dx.doi.org/10.1128/mBio.00358-17

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