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S100A8 inhibits PDGF-induced proliferation of airway smooth muscle cells dependent on the receptor for advanced glycation end-products

BACKGROUND: Airway remodeling is a key feature of asthma, characterized by increased proliferation of airway smooth muscle cells (ASMCs). S100A8 is a calcium-binding protein with a potential to regulate cell proliferation. Here, the effect of exogenous S100A8 protein on the proliferation of ASMCs in...

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Detalles Bibliográficos
Autores principales: Xu, Yu-Dong, Wang, Yu, Yin, Lei-Miao, Peng, Ling-Ling, Park, Gyoung-Hee, Yang, Yong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479006/
https://www.ncbi.nlm.nih.gov/pubmed/28637501
http://dx.doi.org/10.1186/s40659-017-0128-5